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The waning of teriparatide effect on bone formation markers in postmenopausal osteoporosis is associated with increasing serum levels of DKK1

Consequently, inducing ferroptosis has gained attention as a potential therapeutic approach in cancer research (Stockwell et al., 2017)

The peptide functions by mimicking ghrelin, the body's natural "hunger hormone," and binds specifically to GHSR-1a receptors located in the pituitary gland and other tissues throughout the body

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However, phlebotomy cannot be used in patients with significant anemia, malignancy, or hemodynamic instability, and chelation therapy has an inherent risk of toxicity (40, 41)